Nigro-reticular pathway in the rat: an intracellular study

Stimulation of substantia nigra produced short latency excitatory and inhibitory post-synaptic potentials in neurons located in nucleus reticularis gigantocellularis in the reticular formation. These post-synaptic potentials were considered to be monosynaptic on the basis of constant latency at varying stimulus strength. It is suggested that substantia nigra is the source of the inhibition and that excitatory potentials are due to stimulation of cortico-reticular fibers.