Chromosomal DNA homologous to Herpes simplex virus 1 in a mouse L-cell line

Cytological hybridization in situ was used to identify chromosomes carrying DNA sequences homologous to Herpes simplex I (HSV-I) DNA in a HSV-transformed L-cell line. The L-cell karyotype, frequency of chromosome distribution, and possible homology to the normal chromosome complement are given. The major chromosomal sites for transcription of ribosomal RNA (rRNA) were also determined.