Na+ + K+-ATPase in serially excised segments of epileptic monkey cortex

The membrane-bound enzyme Na+ + K+-ATPase was measured in serially excised specimens of cerebral cortex in epileptic and control monkeys. Experimental chronic epileptic cortex showed significantly lower values than controls, as is seen in some other models and human epilepsy, but is different from the increased enzyme values in cobalt and freezing lesion epilepsy.