A possible molecular mechanism for beta-receptor desensitization: experiments and hypotheses

Targeting colorectal cancer via its microenvironment by inhibiting IGF-1 receptor-insulin receptor substrate and STAT3 signaling.

Oncogene·2015

Targeting melanoma with NT157 by blocking Stat3 and IGF1R signaling.

Oncogene·2015

Membrane depolarization combined with Gq-activated G-protein-coupled receptors induce transient receptor potential channel 1 (TRPC1)- dependent potentiation of catecholamine release.

Neuroscience·2011

Status of p53 in human cancer cells does not predict efficacy of CHK1 kinase inhibitors combined with chemotherapeutic agents.

Oncogene·2010

Cisplatin induces PKB/Akt activation and p38(MAPK) phosphorylation of the EGF receptor.

Oncogene·2006

A novel molecular inactivation determinant of voltage-gated CaV1.2 L-type Ca2+ channel.

Neuroscience·2006

Melatonin system integrity shapes gut-brain interaction in schizophrenia-derived microbiota transplant phenotype in mice.

Life sciences·2026

SARS-CoV-2 nucleocapsid protein drives pulmonary injury by enhancing GRP75-dependent ER-mitochondria tethering and reprogramming of alveolar macrophages.

Life sciences·2026

MiR-485-5p targets RGS4 to promote angiogenesis in lower limb ischemia by activating VEGFR-2/AKT/ERK1/2 signaling.

Life sciences·2026

Calpain-2 inhibition prevents pressure overload-induced lysosomal cathepsin release and cardiac hypertrophy.

Life sciences·2026

Organelle contact sites as spatial regulators of lipid fate in adipose tissue metabolic disease.

Life sciences·2026

NR4A1 negatively regulates ferroptosis of pancreatic β-cells induced by Erastin.

Life sciences·2026

The Role of Cellular Glutathione Redox Cycle and Glutathione in the Regulation of Ileum Contractility.

International journal of molecular sciences·2026

Astrocytic TRPC6 protects against cerebral ischemia-reperfusion injury by inhibiting cGAS-STING pathway.

Experimental neurology·2026

Wiring autophagy: Neural circuits regulate lysosomal homeostasis in muscle.

Developmental cell·2026

Deciphering cell state transitions by logical modeling with single-cell transcriptome data.

Journal of molecular cell biology·2026

AMPK as a central regulator of necroptosis: mechanistic insights and therapeutic implications.

Journal of physiology and biochemistry·2026

Integration of RNA-seq and scRNA-seq to investigate the role of cell cycle-related biomarkers in sepsis.

PloS one·2026

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A possible molecular mechanism for beta-receptor desensitization: experiments and hypotheses

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Targeting colorectal cancer via its microenvironment by inhibiting IGF-1 receptor-insulin receptor substrate and STAT3 signaling.

Targeting melanoma with NT157 by blocking Stat3 and IGF1R signaling.

Membrane depolarization combined with Gq-activated G-protein-coupled receptors induce transient receptor potential channel 1 (TRPC1)- dependent potentiation of catecholamine release.

Status of p53 in human cancer cells does not predict efficacy of CHK1 kinase inhibitors combined with chemotherapeutic agents.

Cisplatin induces PKB/Akt activation and p38(MAPK) phosphorylation of the EGF receptor.

A novel molecular inactivation determinant of voltage-gated CaV1.2 L-type Ca2+ channel.

Melatonin system integrity shapes gut-brain interaction in schizophrenia-derived microbiota transplant phenotype in mice.

SARS-CoV-2 nucleocapsid protein drives pulmonary injury by enhancing GRP75-dependent ER-mitochondria tethering and reprogramming of alveolar macrophages.

MiR-485-5p targets RGS4 to promote angiogenesis in lower limb ischemia by activating VEGFR-2/AKT/ERK1/2 signaling.

Calpain-2 inhibition prevents pressure overload-induced lysosomal cathepsin release and cardiac hypertrophy.

Organelle contact sites as spatial regulators of lipid fate in adipose tissue metabolic disease.

NR4A1 negatively regulates ferroptosis of pancreatic β-cells induced by Erastin.

The Role of Cellular Glutathione Redox Cycle and Glutathione in the Regulation of Ileum Contractility.

Astrocytic TRPC6 protects against cerebral ischemia-reperfusion injury by inhibiting cGAS-STING pathway.

Wiring autophagy: Neural circuits regulate lysosomal homeostasis in muscle.

Deciphering cell state transitions by logical modeling with single-cell transcriptome data.

AMPK as a central regulator of necroptosis: mechanistic insights and therapeutic implications.

Integration of RNA-seq and scRNA-seq to investigate the role of cell cycle-related biomarkers in sepsis.

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A possible molecular mechanism for beta-receptor desensitization: experiments and hypotheses

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