Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Calcitonin and the kidney.

P Clifton-Bligh, B Robinson, T Poon

    Progress in Biochemical Pharmacology
    |January 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Pharmacologic calcitonin affects kidney electrolyte handling, particularly phosphate and sodium. In renal failure, calcitonin accumulates, potentially influencing chronic kidney disease bone complications.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Work-related injuries and attendance at a Canadian regional emergency department.

    Occupational medicine (Oxford, England)·2023
    Same author

    Pediatric Cardiology Fellowship Standards for Training in Exercise Medicine and Curriculum Outline.

    Pediatric cardiology·2022
    Same author

    Care of Seniors with Breast Cancer - Treatment Received and Refining Decision Making.

    Clinical oncology (Royal College of Radiologists (Great Britain))·2022
    Same author

    The impact of the COVID-19 pandemic on UK medical education. A nationwide student survey.

    Medical teacher·2021
    Same author

    Outcomes for Patients with Non-metastatic Triple-negative Breast Cancer in New Zealand.

    Clinical oncology (Royal College of Radiologists (Great Britain))·2018
    Same author

    Medullary Thyroid Carcinoma: Survival Analysis and Evaluation of Mutation-Specific Immunohistochemistry in Detection of Sporadic Disease.

    World journal of surgery·2018

    Area of Science:

    • Nephrology
    • Endocrinology
    • Bone Metabolism

    Background:

    • Calcitonin influences renal electrolyte handling (phosphate, sodium) and has kidney receptors linked to adenylate cyclase.
    • Serum calcitonin levels rise in renal failure, suggesting a role in bone disease associated with chronic kidney disease.

    Purpose of the Study:

    • To explore the role of calcitonin in renal function and bone disease in chronic renal failure.
    • To investigate the molecular forms and biologic activity of calcitonin in chronic renal failure.

    Main Methods:

    • Review of existing literature on calcitonin's renal effects.
    • Analysis of calcitonin's presence and forms in serum and urine of patients with renal failure.

    Main Results:

    Related Experiment Videos

    • Pharmacologic calcitonin impacts renal phosphate and sodium handling.
    • Calcitonin accumulates in the serum of patients with renal failure.
    • Multiple molecular forms of calcitonin are found in renal failure, with unknown biologic activity.
    • Immunoreactive calcitonin is detected in urine, but its relation to secretion rates needs further study.

    Conclusions:

    • Calcitonin's renal effects are significant, particularly in electrolyte balance.
    • Accumulated and varied forms of calcitonin in renal failure may contribute to bone disease.
    • Further research is needed to understand the urinary excretion and biologic activity of calcitonin in renal failure.