Differential diagnosis of spindle cell tumours by electron microscopy--personal experience and a review

Electron microscopy has its value and its limitations in refining the histogenetic diagnosis of certain spindle cell tumours. The ultrastructural diagnostic features of neural tumours, muscle tumours, fibrous histiocytomas, fibrosarcomas, monophasic synovial sarcoma and spindle-cell squamous carcinoma are reviewed and illustrated.