Anomalous equilibrium binding properties of high-affinity racemic radioligands

The challenge of drug discovery of a GPCR target: analysis of preclinical pharmacology of histamine H3 antagonists/inverse agonists.

Biochemical pharmacology·2006

Use of an inverse agonist radioligand [3H]A-317920 reveals distinct pharmacological profiles of the rat histamine H3 receptor.

Neuropharmacology·2005

Molecular modeling and pharmacological analysis of species-related histamine H(3) receptor heterogeneity.

Neuropharmacology·2003

Species-related pharmacological heterogeneity of histamine H(3) receptors.

European journal of pharmacology·2002

Short-term inverse-agonist treatment induces reciprocal changes in delta-opioid agonist and inverse-agonist binding capacity.

Molecular pharmacology·2001

An integrated structural and functional profiling approach uncovers the mechanisms of pregnane X receptor binding and activation by pharmaceutical and environmental compounds.

Molecular pharmacology·2026

Anchored kinase and phosphatase signaling networks in amyloid β-induced synaptic dysfunction.

Molecular pharmacology·2026

Where are peptide ligands of potassium channels sourced from?

Molecular pharmacology·2026

Regulation of organic anion transporting polypeptide 1B1 transport function by lysine deacetylase 6.

Molecular pharmacology·2026

Neuroprotective in vitro effects of histone deacetylase 6-selective inhibitor SW-100 toward oxaliplatin-derived toxicity.

Molecular pharmacology·2026

Emerging roles of platelet DNA in cancer detection and noninvasive prenatal testing.

Molecular pharmacology·2026

Advanced statistical and nonlinear modeling approach for dye adsorption onto a sustainable Casuarina-based microporous adsorbent.

International journal of phytoremediation·2026

Dual-Enhanced Electrochemiluminescence Imaging on a Monolayer Film of Nanoreactors for Probing Cell-Matrix Interaction.

Chemical & biomedical imaging·2026

Oligomerisation Drives Internal Cavity Formation and Conformational Heterogeneity in Mixed Triton X-100/Tyloxapol Micelles.

Small science·2026

Deciphering Anion-Induced Dynamic Heterogeneity of Electrochemiluminescence on Single Gold Microplates via Multi-Resolved Imaging.

Chemical & biomedical imaging·2026

Hidden tellurium speciation resolves the paradox of infinite Te chains in LaCu x Te2.

Chemical science·2026

Effects of Syringaldehyde/Gum Arabic Composite Chitosan Thermochromic Microcapsules on the Coating Properties of Basswood Surface.

Polymers·2026

Related Experiment Videos

Anomalous equilibrium binding properties of high-affinity racemic radioligands

Related Concept Videos

The challenge of drug discovery of a GPCR target: analysis of preclinical pharmacology of histamine H3 antagonists/inverse agonists.

Use of an inverse agonist radioligand [3H]A-317920 reveals distinct pharmacological profiles of the rat histamine H3 receptor.

Molecular modeling and pharmacological analysis of species-related histamine H(3) receptor heterogeneity.

Species-related pharmacological heterogeneity of histamine H(3) receptors.

Short-term inverse-agonist treatment induces reciprocal changes in delta-opioid agonist and inverse-agonist binding capacity.

An integrated structural and functional profiling approach uncovers the mechanisms of pregnane X receptor binding and activation by pharmaceutical and environmental compounds.

Anchored kinase and phosphatase signaling networks in amyloid β-induced synaptic dysfunction.

Where are peptide ligands of potassium channels sourced from?

Regulation of organic anion transporting polypeptide 1B1 transport function by lysine deacetylase 6.

Neuroprotective in vitro effects of histone deacetylase 6-selective inhibitor SW-100 toward oxaliplatin-derived toxicity.

Emerging roles of platelet DNA in cancer detection and noninvasive prenatal testing.

Advanced statistical and nonlinear modeling approach for dye adsorption onto a sustainable Casuarina-based microporous adsorbent.

Dual-Enhanced Electrochemiluminescence Imaging on a Monolayer Film of Nanoreactors for Probing Cell-Matrix Interaction.

Oligomerisation Drives Internal Cavity Formation and Conformational Heterogeneity in Mixed Triton X-100/Tyloxapol Micelles.

Deciphering Anion-Induced Dynamic Heterogeneity of Electrochemiluminescence on Single Gold Microplates via Multi-Resolved Imaging.

Hidden tellurium speciation resolves the paradox of infinite Te chains in LaCu x Te2.

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Anomalous equilibrium binding properties of high-affinity racemic radioligands

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