Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Virology and immune mechanisms.

T C Merigan

    Cancer
    |March 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Chronic infections like Epstein-Barr virus and hepatitis B virus, along with immunosuppression, increase cancer risk. Understanding these links aids in developing new cancer detection and control strategies.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Nonviral interferon inducers.

    The Journal of general physiology·2009
    Same author

    Effect of therapeutic immunization with HIV type 1 recombinant glycoprotein 160 ImmunoAG vaccine in HIV-infected individuals with CD4+ T cell counts of >or=500 and 200-400/mm3 (AIDS Clinical Trials Group Study 246/946).

    AIDS research and human retroviruses·2001
    Same author

    Functional correlates of insertion mutations in the protease gene of human immunodeficiency virus type 1 isolates from patients.

    Journal of virology·2001
    Same author

    Variants other than aspartic acid at codon 69 of the human immunodeficiency virus type 1 reverse transcriptase gene affect susceptibility to nuleoside analogs.

    Antimicrobial agents and chemotherapy·2001
    Same author

    Anti-HIV type 1 activity of 3'-fluoro-3'-deoxythymidine for several different multidrug-resistant mutants.

    AIDS research and human retroviruses·2001
    Same author

    High degree of interlaboratory reproducibility of human immunodeficiency virus type 1 protease and reverse transcriptase sequencing of plasma samples from heavily treated patients.

    Journal of clinical microbiology·2001

    Area of Science:

    • Oncology
    • Virology
    • Immunology

    Background:

    • Epstein-Barr virus (EBV) and hepatitis B virus (HBV) are linked to specific human neoplasms.
    • Immunosuppression, whether congenital or iatrogenic (e.g., organ transplant recipients, chemotherapy, radiation), elevates susceptibility to certain malignancies.

    Purpose of the Study:

    • To explore the association between viral infections and cancer development.
    • To investigate the role of immunosuppression in malignancy.
    • To identify potential new avenues for cancer control and detection.

    Main Methods:

    • Review of existing literature on viral oncogenesis.
    • Analysis of epidemiological data on cancer incidence in immunosuppressed populations.
    • Correlation of immunosuppressive therapy with malignancy rates.

    Related Experiment Videos

    Main Results:

    • Chronic EBV and HBV infections are associated with specific cancers.
    • Immunosuppressed individuals exhibit a higher incidence of particular malignancies.
    • Findings suggest a mechanistic link between immune status and tumor development.

    Conclusions:

    • Viral infections and immunosuppression are significant factors in human cancer.
    • These associations offer insights into tumor development mechanisms.
    • There is a need to consider limitations on immunosuppressive therapy to mitigate cancer risk.