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Development of a Hepatitis B Virus Reporter System to Monitor the Early Stages of the Replication Cycle
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Development of a Hepatitis B Virus Reporter System to Monitor the Early Stages of the Replication Cycle

Published on: February 1, 2017

Expression of the hepatitis B virus surface antigen gene in cell culture by using a simian virus 40 vector

A M Moriarty, B H Hoyer, J W Shih

    Proceedings of the National Academy of Sciences of the United States of America
    |April 1, 1981
    PubMed

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    Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...