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Age-related changes of cyclic nucleotide levels in rat brain regions
Mechanisms of Ageing and Development
|March 1, 1981
Abstract:
Cyclic AMP and cyclic GMP levels were measured in seven brain areas of rats 4-30 months old. In several brain areas cyclic nucleotides were higher in 4-month-old rats than in rats 12 months old or older. On the other hand, in the hypothalamus cyclic GMP levels were decreased only in 30-month-old rats, a pattern of onset similar to that of senile deterioration.
