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Updated: Aug 18, 2026

Introduction to Solid Supported Membrane Based Electrophysiology
Published on: May 11, 2013
Transport noise in membranes. Current and voltage fluctuations at equilibrium
Abstract:
A formulism is described for the treatment of noise resulting from the transport of ions in channels containing an arbitrary number of activation energy barriers. The analysis is based on Nyquist's theorem and is therefore restricted to fluctuations around the equilibrium state. Within this limit the spectral intensities of current and voltage noise are given by the frequency-dependent admittance, which in turn is closely linked to the relaxation-time spectrum of the transport system. Explicit expressions for the spectral intensity of current noise are derived for channels with two and three energy barriers. The analysis may be used to predict the spectral intensity of noise from the gating system in nerve.
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