Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Endogenous pyrogen formation by bone marrow cells].

O M Efremov, A V Sorokin, O A El'kina

    Biulleten' Eksperimental'Noi Biologii I Meditsiny
    |January 1, 1978
    PubMed
    Summary

    Rabbit bone marrow cells produce endogenous pyrogen when stimulated by bacterial lipopolysaccharide. Optimal pyrogen release occurs in medium No. 199 with 15% homologous serum, suggesting bone marrow cells

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Serum Beta-Defensin-2 is a biomarker for psoriasis but not subclinical atherosclerosis: Role of IL17a, PI-3 kinase and Rac1.

    JEADV clinical practice·2024
    Same author

    Novel biocatalysts based on enzymes in complexes with nano- and micromaterials.

    Biophysical reviews·2023
    Same author

    Update of ion-optical system of neutral beam of Tokamak à Configuration Variable.

    The Review of scientific instruments·2020
    Same author

    [The use of immunomodulators, antioxidants and hepatoprotectors for the correction of the liver, erythrocites and the immune system disorders in chronic ethanol intoxication].

    Biomeditsinskaia khimiia·2018
    Same author

    Excimer Emission of Acridine Orange Adsorbed on Gadolinium-Yttrium Orthovanadate Nanoparticles.

    Journal of fluorescence·2018
    Same author

    [Desadaptive Reaction and Development of Arterial Hypertension in Conditions of Professional Stress].

    Kardiologiia·2017

    Area of Science:

    • Immunology
    • Hematology

    Context:

    • Bacterial lipopolysaccharide (LPS) is a potent stimulator of inflammatory responses.
    • Endogenous pyrogens mediate fever in response to infection or inflammation.

    Purpose:

    • To investigate the role of rabbit bone marrow cells in endogenous pyrogen production.
    • To identify optimal conditions for pyrogen release from bone marrow cells.

    Summary:

    • Rabbit bone marrow cells were stimulated with bacterial lipopolysaccharide (LPS).
    • Optimal endogenous pyrogen (EP) release was observed in Medium No. 199 with 15% homologous serum.
    • These findings suggest bone marrow cells contribute to EP formation and the fever mechanism.

    Impact:

    • Elucidates the cellular source of endogenous pyrogen in rabbits.
    • Provides insights into the inflammatory mechanisms involving bone marrow.
    • Contributes to understanding the pathophysiology of fever.

    Related Experiment Videos