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[Experimental amebiasis: effect of PGE1 on rats infested with Entamoeba histolytica]
Annali Sclavo; Rivista Di Microbiologia E Di Immunologia
|September 1, 1980
Abstract:
The authors have studied the effects of PGE1 on rats (Wistar strain) infected with Entamoeba histolytica, and inoculated with PGE1 either in massive dosage and killed after 3-5 and 7 days, or with daily minimum quantity of PGE1 and killed on days 7 and 15 after inoculation. The results show an inhibition effect of PGE1 on development and survival of amoebae in the coecum of rats inoculated with the two modalities described above. The fractionated dosage gives better results and less side effects.