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Pathogenicity of two strains of Mycoplasma gallisepticum in broilers

R Rodriguez, S H Kleven

    Avian Diseases
    |October 1, 1980
    PubMed

    Insights

    The Mycoplasma gallisepticum (MG) R strain caused more severe airsacculitis and lower antibody titers in chickens than the F strain. Vaccination with ND-IB vaccine worsened MG lesions and reduced body weight when combined with the R strain.

    Area of Science:

    • Veterinary Medicine
    • Pathogen Research
    • Poultry Health

    Background:

    • Mycoplasma gallisepticum (MG) is a significant avian pathogen.
    • Understanding strain pathogenicity is crucial for effective disease control in poultry.

    Purpose of the Study:

    • To compare the pathogenicity of Mycoplasma gallisepticum (MG) strains F and R.
    • To evaluate the impact of concurrent vaccination on MG infection outcomes.

    Main Methods:

    • Two laboratory trials were conducted exposing chickens to MG strains F and R.
    • Airsacculitis incidence and severity were assessed.
    • Antibody production (hemagglutination-inhibition titers) and body weights were measured.

    Main Results:

    • The R strain induced significantly higher airsacculitis incidence and severity compared to the F strain (P < 0.05).
    • Chickens exposed to the R strain had lower MG antibody titers than those exposed to the F strain.
    • Concurrent vaccination with Newcastle disease-infectious bronchitis vaccine exacerbated MG lesions and reduced body weight, particularly with the R strain.

    Conclusions:

    • Mycoplasma gallisepticum strain R is more pathogenic than strain F.
    • Concurrent vaccination can increase disease severity and negatively impact growth in chickens infected with MG.

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