Variation in spermatozoal levels of phosphoglycerate kinase-2 in mice

Litter size differences exist between inbred strains of mice with high and low spermatozoal phosphoglycerate kinase-2 activity, but an examination of these two variables in recombinant inbred lines between the two strains suggest that the variables are not related. An examination of spermatozoal cAMP concentrations in these recombinant inbred lines demonstrated no correlation with litter size. Furthermore, spermatozoal cAMP concentrations were demonstrated to be under multigenic control.