Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Myasthenia Gravis: Diagnostic Tests01:15

Myasthenia Gravis: Diagnostic Tests

3.3K
Myasthenia gravis is an autoimmune condition affecting neuromuscular transmission, causing generalized weakness in skeletal muscles. Initial diagnoses rely on patients' signs, symptoms, and medical history. The challenge lies in distinguishing myasthenia from other muscular dystrophies. An important diagnostic feature is the significant improvement of symptoms after administering anticholinesterase inhibitors.
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
3.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Immunosuppressive treatment of motor neuron syndromes. Attempts to distinguish a treatable disorder.

Archives of neurologyยท1994
Same author

The Bruns-Garland syndrome (diabetic amyotrophy). Revisited 100 years later.

Archives of neurologyยท1991
Same author

Diagnosis of Maryland/German familial amyloidotic polyneuropathy using allele-specific, enzymatically amplified, genomic DNA.

Annals of neurologyยท1990
Same author

Chronic inflammatory demyelinating polyradiculoneuropathy. Clinical characteristics, course, and recommendations for diagnostic criteria.

Archives of neurologyยท1989
Same author

Scapuloperoneal neuropathy: a distinct clinicopathologic entity.

Journal of the neurological sciencesยท1988
Same author

Comparison of the effects of continuous subcutaneous infusion and split-mixed injection of insulin on nerve function in type I diabetes mellitus.

Journal of the neurological sciencesยท1987

Related Experiment Video

Updated: May 6, 2026

Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis
08:16

Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis

Published on: March 4, 2014

33.4K

Electrodiagnosis in neuromuscular disorders.

J R Warmolts

    Annals of Internal Medicine
    |November 1, 1981
    PubMed
    Summary

    Nerve conduction studies and electromyography help diagnose nerve and muscle diseases. These techniques differentiate disorders affecting motor neurons, nerves, synapses, or muscles, identifying focal or generalized issues and disease progression.

    Area of Science:

    • Neurology
    • Clinical Neurophysiology

    Background:

    • Nerve conduction studies (NCS) and needle electromyography (EMG) are essential diagnostic tools.
    • Objective verification of nerve and muscle disease is crucial for accurate diagnosis.

    Purpose of the Study:

    • To explore how pathological changes in nerves and muscles create electrical abnormalities.
    • To guide clinicians in differentiating various neuromuscular disorders.

    Main Methods:

    • Utilizing combined nerve conduction and stimulation studies.
    • Employing needle electromyography for detailed muscle analysis.

    Main Results:

    • Demonstrating the ability of NCS and EMG to detect and characterize neuromuscular pathologies.
    • Providing a framework for distinguishing between motor neuron, peripheral nerve (axon/myelin), synapse, and muscle involvement.

    More Related Videos

    Assessment of Neuromuscular Function Using Percutaneous Electrical Nerve Stimulation
    07:53

    Assessment of Neuromuscular Function Using Percutaneous Electrical Nerve Stimulation

    Published on: September 13, 2015

    22.1K
    Measuring Neuromuscular Junction Functionality
    10:40

    Measuring Neuromuscular Junction Functionality

    Published on: August 6, 2017

    17.7K

    Related Experiment Videos

    Last Updated: May 6, 2026

    Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis
    08:16

    Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis

    Published on: March 4, 2014

    33.4K
    Assessment of Neuromuscular Function Using Percutaneous Electrical Nerve Stimulation
    07:53

    Assessment of Neuromuscular Function Using Percutaneous Electrical Nerve Stimulation

    Published on: September 13, 2015

    22.1K
    Measuring Neuromuscular Junction Functionality
    10:40

    Measuring Neuromuscular Junction Functionality

    Published on: August 6, 2017

    17.7K

    Conclusions:

    • NCS and EMG are invaluable for objectively assessing neuromuscular function.
    • These electrodiagnostic techniques aid in localizing lesions (focal vs. generalized) and assessing disease activity (ongoing damage vs. repair).