[Synthesis of a high-capacity immunosorbent based on a cellulose suspension]

A method is suggested for preparation of an immunosorbent on the basis of cellulose suspension. Antigen was coupled to periodate-oxidized cellulose via aldehyde groups. Optimal conditions (time of oxidation, amount of an oxidant, quantity of protein antigen added) for immunosorbent synthesis were determined. The amount of antibodies bound to the immunosorbent was approximately equal to the weight of the immunosorbent (up to 950 mg of antibodies per 1 g sorbent). Thus each molecule of antigen coupled to cellulose bound 5-8 molecules of antibodies.