Minimal medullary droplets in DOCA-induced potassium depletion of rats

When potassium depletion is induced in rats administering desoxycorticosterone acetate instead of restricting potassium in the diet, the droplet accumulation in medullary cells is reduced, despite the similar degree and duration of potassium depletion. This finding indicates that the accumulation of droplets is more dependent on the inducing agent than on the severity or duration of potassium depletion.