Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Polypeptide hormones and the prostate.

M M Webber

    Progress in Clinical and Biological Research
    |January 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Insulin and prolactin directly impact prostate growth and function, enhancing testosterone's effects. Further research is needed to understand their intracellular mechanisms and interactions in prostate health and disease.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Hot and not-so-hot females: reproductive state and thermal preferences of female Arizona Bark Scorpions (Centruroides sculpturatus).

    Journal of evolutionary biology·2014
    Same author

    Retinoids, vitamin D, invasion, and metastasis.

    Current oncology (Toronto, Ont.)·2012
    Same author

    Evaluation of the chemopreventive potential of retinoids using a novel in vitro human prostate carcinogenesis model.

    Mutation research·2001
    Same author

    N-(4-hydroxyphenyl)retinamide (4-HPR) decreases neoplastic properties of human prostate cells: an agent for prevention.

    Mutation research·2001
    Same author

    The role of alpha 6 beta 1 integrin and EGF in normal and malignant acinar morphogenesis of human prostatic epithelial cells.

    Mutation research·2001
    Same author

    Human cell lines as an in vitro/in vivo model for prostate carcinogenesis and progression.

    The Prostate·2001
    Same journal

    DNA homology and chromosome stability: a sensitive yeast genetic system for identifying double-stranded DNA damage.

    Progress in clinical and biological research·2018
    Same journal

    Endotoxin and sepsis: molecular mechanisms of pathogenesis, host resistance, and therapy. Proceedings of the 4th Conference of the International Endotoxin Society. Nagoya, Japan, October 23-27, 1996.

    Progress in clinical and biological research·1998
    Same journal

    The pathogenic role of LBP in gram-negative sepsis and septic shock.

    Progress in clinical and biological research·1998
    Same journal

    The role of interleukin 6 in endotoxin-induced inflammatory responses.

    Progress in clinical and biological research·1998
    Same journal

    Role of nitric oxide and reactive oxygen species in endotoxin shock.

    Progress in clinical and biological research·1998
    Same journal

    Interaction of lipopolysaccharide with a mammalian lyso-phosphatidate acyltransferase (LPAAT) transfected into E. coli, and effect of lisofylline on LPAAT transfected into mammalian cells.

    Progress in clinical and biological research·1998
    See all related articles

    Area of Science:

    • Endocrinology
    • Urology
    • Cell Biology

    Background:

    • The roles of insulin and prolactin in prostate physiology are not fully elucidated.
    • Understanding hormonal influences on prostatic epithelium is crucial for addressing growth-related conditions.

    Purpose of the Study:

    • To investigate the direct and indirect effects of insulin and prolactin on prostatic epithelium.
    • To explore the impact of these hormones on cell multiplication and ornithine decarboxylase activity.
    • To identify knowledge gaps regarding intracellular events and interactions with other hormones.

    Main Methods:

    • The study focuses on the functional and growth-related effects of insulin and prolactin on prostatic cells.
    • Analysis includes assessing cell multiplication and ornithine decarboxylase activity.

    Related Experiment Videos

  • The research examines the potentiation of testosterone's effects by insulin and prolactin.

    • Main Results:

    • Insulin and prolactin exert direct effects on prostatic epithelium growth and function.
    • These hormones indirectly enhance testosterone's influence on prostate cells.
    • Both insulin and prolactin stimulate cell proliferation and increase ornithine decarboxylase activity.

    Conclusions:

    • Insulin and prolactin are significant regulators of prostatic epithelium.
    • Further research is essential to clarify intracellular signaling pathways and hormonal interactions.
    • Understanding these hormones is key to comprehending normal and abnormal prostate growth.