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Related Experiment Videos

Nipple discharge from the breast.

T M Murad, G Contesso, H Mouriesse

    Annals of Surgery
    |March 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Abnormal nipple discharge is rare but can indicate serious conditions. Surgery is required for 23% of cases, with malignancy found in 4.8% of all nipple discharge patients.

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    Area of Science:

    • Oncology
    • General Surgery
    • Pathology

    Background:

    • Abnormal nipple discharge is an uncommon reason for mammary consultations, representing 3-5% of cases.
    • This study evaluates patients with symptomatic, spontaneous nipple discharge requiring surgical intervention.

    Purpose of the Study:

    • To analyze the causes and outcomes of surgically treated nipple discharge.
    • To determine the incidence of malignancy in patients with nipple discharge.

    Main Methods:

    • Retrospective review of 267 patients surgically treated for primary nipple discharge at Institut Gustave-Roussay (IGR) between 1960 and 1974.
    • Analysis of 1,145 total nipple discharge cases treated during the same period.

    Main Results:

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  • Fibrocystic disease and duct ectasia were the most common benign causes (42%).
  • Malignancy was diagnosed in 21% of surgically treated patients and 4.8% of all nipple discharge cases.
  • Malignant discharge patients were, on average, ten years older than those with benign lesions; 60% of patients with discharge and a mass had malignancy.

    • Conclusions:

    • While often benign, abnormal nipple discharge necessitates thorough investigation due to the significant incidence of malignancy.
    • Age and the presence of an associated mass are critical indicators for potential malignancy in patients with nipple discharge.