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[Paracetamol in oral solution: effectiveness against fever and tolerance in children with measles (author's transl)]
La Semaine Des Hopitaux : Organe Fonde Par L'Association D'Enseignement Medical Des Hopitaux De Paris
|March 18, 1982
Insights
New oral paracetamol effectively reduced fever in children with measles. This safe and well-tolerated medication offers a promising treatment option for pediatric hyperthermia.
Area of Science:
- Pediatrics
- Pharmacology
- Infectious Diseases
Context:
- Measles is a common childhood illness often accompanied by fever (hyperthermia).
- Effective fever management is crucial for comfort and preventing complications in children with measles.
- Oral paracetamol solution is a recently available formulation for pediatric use.
Purpose:
- To evaluate the efficacy and safety of oral paracetamol solution in reducing fever in children with measles.
- To assess the impact of paracetamol on rectal temperatures during the pre-eruptive and eruptive stages of measles.
Summary:
- Thirty-one children with measles-induced hyperthermia received a single dose of oral paracetamol solution.
- Rectal temperatures were monitored for six hours post-administration.
- Significant and satisfactory reductions in temperature were observed, with no adverse side-effects reported.
Impact:
- Oral paracetamol solution demonstrates significant efficacy in managing hyperthermia associated with measles in children.
- The medication is well-tolerated, indicating a favorable safety profile for pediatric use.
- This study supports the use of oral paracetamol as a safe and effective antipyretic for febrile children with measles.
Abstract:
Paracetamol in oral solution, which has become recently available, was given to thirty-one children with hyperthermia due to measles either in the pre-eruptive or the eruptive stages. Rectal temperatures were recorded at regular intervals over the first six hours following the ingestion of a single dose. Falls in temperature were significant and satisfactory. No adverse side-effects were seen.