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[Recent considerations on systemic lupus erythematosus (author's transl)]
Abstract:
Recent advances have shown that the pathogenesis of systemic lupus erythematosus involves a number of interacting factors. Renal involvement is frequent and is one of the leading factor in the prognosis. Renal histopathology is most important in the management of patients. Immunologic tests may help in the diagnosis and also in the evaluation of diseases activity. Although survival has improved dramatically with the use of corticosteroids, there is as yet no evidence that immunosuppressive drugs may be beneficial.