Pertechnetate imaging following cimetidine administration in Meckel's diverticulum of the ileum

The demonstration of secretory gastric mucosa in Meckel's diverticulum of the ileum in patients undergoing radionuclide imaging with 99mTc sodium pertechnetate is greatly improved with the prior administration of cimetidine. This results in enhanced accumulation of pertechnetate in the gastric mucosa along with reduced excretion of the radionuclide into the gastric lumen and, consequently, less intestinal radioactivity.