Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Increased pyrophosphate rib uptake: clinical correlation.

L J Talarico, O F Shalaby, H M Abdel-Dayem

    Journal of Surgical Oncology
    |March 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Importance of Tc-99m sulfur colloid liver-spleen scans performed before indium-111 labeled leukocyte imaging for localization of abdominal infection.

    Clinical nuclear medicine·2005
    Same author

    Thyroid cancer follow-up.

    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·2004
    Same author

    Use of iodine-123 as a diagnostic tracer for neck and whole-body scanning in patients with well-differentiated thyroid cancer.

    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·2004
    Same author

    Breast carcinoma.

    Nuclear medicine review. Central & Eastern Europe·2003
    Same author

    SPECT brain perfusion findings in mild or moderate traumatic brain injury.

    Nuclear medicine review. Central & Eastern Europe·2003
    Same author

    Neck and whole-body scanning with 5-mCi dose of (123)I as diagnostic tracer in patients with well-differentiated thyroid cancer.

    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·2001

    Bone scans can detect rib metastases, but interpretation requires careful analysis of uptake patterns and other skeletal findings. Differentiating benign from malignant rib uptake is crucial for accurate diagnosis.

    Area of Science:

    • Nuclear Medicine
    • Radiology
    • Oncology

    Background:

    • Bone scans are frequently used to detect skeletal metastases.
    • Increased uptake in ribs on bone scans can be challenging to interpret.
    • Distinguishing benign from malignant causes of rib uptake is clinically important.

    Purpose of the Study:

    • To evaluate the incidence and significance of increased rib uptake on bone scans.
    • To determine the accuracy of bone scans in identifying rib metastases.
    • To analyze factors influencing the interpretation of rib uptake.

    Main Methods:

    • Retrospective review of 270 bone scans from 231 patients.
    • Correlation of increased rib uptake with radiological findings and clinical data.
    • Analysis of uptake characteristics: localization, distribution, and association with other skeletal abnormalities.

    Related Experiment Videos

    Main Results:

    • Abnormal rib uptake occurred in 23% of patients with malignant disease and 10% with benign conditions.
    • True positive rib metastases were identified in 34% of malignant cases, often multiple.
    • Benign causes accounted for 20% of uptake, with 46% being indefinite; early metastases were suspected in 17% of these.
    • Missed rib metastases occurred in only 1.1% of cases (multiple myeloma, direct lung carcinoma extension).

    Conclusions:

    • Increased rib uptake on bone scans requires careful evaluation considering uptake patterns and clinical context.
    • Bone scans are highly sensitive for detecting rib metastases, with a low rate of missed diagnoses.
    • Further investigation is warranted for indefinite rib uptake findings to differentiate benign from early malignant causes.