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[Chemotherapy of bronchogenic cancer (author's transl)]
Abstract:
This report summarizes our experience with protocols "ACLI" and with alternative combinations such as ifosfamide plus etoposide in the chemotherapy of inoperable bronchogenic carcinoma. Using the "ACO"-protocols and consolidating irradiation, 77% complete remissions were achieved in patients with limited disease (median survival of 21 months). Patients with extensive disease (50% complete remissions) had a median survival of 10 months. The survival data point to a plateau after 30 months, suggesting that approximately 20% of limited disease patients may achieve long-term survival. Relapse patterns are analyzed.