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Piperidylalkylindoles. 1. Hypotensive activity of 3-[2-(phenoxypiperidyl)ethyl]indoles
Journal of Medicinal Chemistry
|March 1, 1978
Abstract:
A series of 3-[2-(phenoxypiperidyl)-ethyl]indoles was synthesized and evaluated for hypotensive activity in the spontaneous hypertensive rat. Maximum hypotensive activity appeared when the phenoxy substituent was para substituted and occupied the 4 position of the piperidine ring.