Endobronchial Hodgkin's disease

Area of Science:

• Pulmonology
• Oncology

Background:

• Nodular sclerosing Hodgkin's disease is a type of lymphoma.
• Endobronchial involvement in Hodgkin's disease is an uncommon presentation.

Observation:

• A 26-year-old woman with known Hodgkin's disease presented with chest pain and a lung infiltrate.
• Fiberoptic bronchoscopy revealed nodular lesions within the bronchi and at the carina.
• Biopsy confirmed Hodgkin's disease in the endobronchial lesions.

Findings:

• Sequential systemic chemotherapy was administered to the patient.
• Follow-up bronchoscopy demonstrated complete resolution of the endobronchial lesions.
• The patient achieved and maintained a complete remission for 24 months.

Implications:

• This case highlights the possibility of endobronchial spread in Hodgkin's disease.
• Systemic chemotherapy can be effective in treating endobronchial Hodgkin's disease.
• Successful treatment leads to long-term remission and symptom resolution.