Related Experiment Videos
Adenovirus bronchiolitis in Manitoba: epidemiologic, clinical, and radiologic features
Insights
Adenovirus (ADV) bronchiolitis significantly impacts native Indian children, causing acute complications and long-term lung issues. Further research is needed to understand its prevalence and effects on airway function.
Area of Science:
- Pediatrics
- Infectious Diseases
- Pulmonology
Background:
- Adenovirus (ADV) is a significant cause of bronchiolitis in children.
- Native Indian children appear to have a higher susceptibility to ADV bronchiolitis.
- Bronchiolitis can lead to acute complications and potentially chronic pulmonary disorders.
Purpose of the Study:
- To review the clinical experience with adenovirus bronchiolitis in hospitalized children.
- To identify risk factors and outcomes, particularly in native Indian children.
- To highlight the association between ADV bronchiolitis and chronic pulmonary issues in pediatrics.
Main Methods:
- Retrospective review of 41 children hospitalized for adenovirus bronchiolitis between 1974 and 1978.
- Analysis of patient demographics, clinical presentation, complications, and radiographic findings.
- Evaluation of radiological follow-up for long-term pulmonary sequelae.
Main Results:
- The majority of patients (78%) were native Indian children aged 4-12 months.
- Acute complications occurred in 43.9% of patients, with all five fatal cases (12.2%) in native children.
- Initial chest X-rays revealed lobar consolidation in 85.4%, and 64% of those with follow-up showed subsequent pneumonias or chronic changes.
Conclusions:
- Adenovirus bronchiolitis poses a significant health burden on native Indian children, with a high rate of complications and mortality.
- The study suggests a link between ADV bronchiolitis and the development of chronic pulmonary disorders in pediatric survivors.
- Further investigation is warranted to elucidate the reasons for ADV bronchiolitis predilection in this population and its long-term respiratory effects.
Abstract:
We reviewed our experience with 41 children hospitalized from 1974 to 1978 for adenovirus (ADV) bronchiolitis. Thirty-two patients (78 percent) were native Indians between four and 12 months old. In 18 of the 41 patients (43.9 percent) acute complications developed. The five fatal cases (12.2 percent) were confined to native children. The initial chest roentgenograms showed lobar consolidation in 35 patients (85.4 percent). Atelectasis developed in five (12.2 percent) during hospitalization. Sixteen of 25 patients (64 percent) with adequate radiologic follow-up examination had subsequent pneumonias or showed residual chronic changes. The reasons for the predilection of ADV bronchiolitis in native Indian children and the precise effect on subsequent airway function in survivors are unknown and require further study. We emphasize the importance of ADV as a cause of bronchiolitis in native Indian children. Furthermore, this report focuses attention on the contribution of this disease to the spectrum of chronic pulmonary disorders in the pediatric group.