Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Technetium scanning in Kaposi's sarcoma and its simulators.

R Gunnoe, J Kalivas

    Journal of the American Academy of Dermatology
    |April 1, 1982
    PubMed
    Summary

    Diagnosing leg plaques like Kaposi's sarcoma can be tricky. Technetium scans help differentiate between Kaposi's sarcoma, pseudo-Kaposi's sarcoma, and atrophie blanche.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Gestalt theory and psychiatry.

    Journal of the Royal Society of Medicine·2010
    Same author

    Non-sexist grammar in medical literature.

    Journal of the Royal Society of Medicine·2010
    Same author

    Tolerability of high-dose topical tretinoin: the Veterans Affairs Topical Tretinoin Chemoprevention Trial.

    The British journal of dermatology·2009
    Same author

    Reliability of counting actinic keratoses before and after brief consensus discussion: the VA topical tretinoin chemoprevention (VATTC) trial.

    Archives of dermatology·2001
    Same author

    Is ivermectin safe for humans?

    International journal of dermatology·1999
    Same author

    Once-weekly fluconazole (450 mg) for 4, 6, or 9 months of treatment for distal subungual onychomycosis of the toenail.

    Journal of the American Academy of Dermatology·1998

    Area of Science:

    • Dermatology
    • Vascular Medicine
    • Diagnostic Imaging

    Background:

    • Ulcerated purple plaques on the legs present a diagnostic challenge, with differential diagnoses including Kaposi's sarcoma, stasis dermatitis, atrophie blanche (livedoid vasculitis), and acroangiodermatitis of Favre-Chaix (pseudo-Kaposi's sarcoma).
    • Clinical and histopathological features can overlap significantly, making definitive diagnosis difficult even with skin biopsy.

    Purpose of the Study:

    • To evaluate the utility of technetium isotope scanning as an adjunctive diagnostic tool for differentiating between Kaposi's sarcoma, pseudo-Kaposi's sarcoma, and atrophie blanche.
    • To highlight the diagnostic challenges posed by similar clinical presentations of these leg dermatoses.

    Main Methods:

    • Case series describing three patients with pseudo-Kaposi's sarcoma, one with Kaposi's sarcoma, and two with atrophie blanche.
    • Clinical and histopathological review of all cases.
    • Performance of technetium isotope scanning in all patients.

    Main Results:

    • Technetium scans were positive in both Kaposi's sarcoma and pseudo-Kaposi's sarcoma.
    • Technetium scans were negative in atrophie blanche.
    • The study underscores the clinical and histopathological similarities that necessitate further confirmatory investigations.

    Conclusions:

    • Technetium isotope scanning may serve as a valuable non-invasive tool to help distinguish between Kaposi's sarcoma/pseudo-Kaposi's sarcoma and atrophie blanche.
    • Further studies are warranted to confirm the sensitivity and specificity of technetium scanning in these conditions.

    Related Experiment Videos