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Related Experiment Videos

Prevention and control of mousepox.

J D Small, A E New

    Laboratory Animal Science
    |October 1, 1981
    PubMed
    Summary

    Preventing mousepox requires institutional awareness and strict policies for controlling ectromelia virus in mice and tissues. Early detection and open communication are crucial for managing this serious disease in research settings.

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    Area of Science:

    • Veterinary Pathology
    • Laboratory Animal Science
    • Infectious Disease Control

    Background:

    • Mousepox, caused by the ectromelia virus, poses a significant threat to research involving mice and mouse tissues.
    • Effective prevention and control strategies are essential for maintaining the integrity of research models and animal welfare.

    Purpose of the Study:

    • To outline essential components of institutional policies for the prevention and control of mousepox.
    • To emphasize the importance of awareness, surveillance, and communication in managing ectromelia virus outbreaks.

    Main Methods:

    • Implementing institutional management policies for disease-free entry of mice and tissues.
    • Establishing active disease surveillance programs for incoming animals and tissues.
    • Maintaining comprehensive records of animal and tissue receipts.
    • Fostering open communication among investigators regarding disease presence.

    Main Results:

    • Recognition of mousepox as an institutional problem requiring a unified approach.
    • Necessity of rapid notification to all involved investigators upon diagnosis.
    • Confirmation of diagnosis and dissemination of information to the scientific community.

    Conclusions:

    • Institutional policies must ensure mice and mouse tissues entering facilities are free of ectromelia virus.
    • Control measures include disease surveillance, record-keeping, and open communication.
    • Strategies for elimination may involve euthanasia of replaceable mice or vaccination of valuable stock.

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