[The problem of sequential cancers after antineoplastic chemotherapy or radiotherapy]

It is reported on 4 patients who in a period of 2 to 14 years after successful therapy of a malignant tumour using the therapy with cytostatics and (or) radiotherapy fell ill with a genuine secondary neoplasia. A connection of the therapeutic procedures mentioned with the repeated tumour induction is obvious, a genetic disposition (cancer diseases in parents and brothers and sisters) might favourably cooperate in three of the cases mentioned. It is referred to the necessity of strongest indication to the therapy with cytostatics and ionising rays.