Pregnancy following cytomegalovirus mononucleosis

A case of cytomegalovirus heterophile-negative mononucleosis seen in a primary care setting is reported. The patient was a young woman with fever that had persisted for 24 days, and with relative bradycardia, hepatosplenomegaly, suboccipital lymphadenopathy and a rash. Diagnosis was based on clinical and hematological findings which included relative and absolute lymphocytosis with atypical lymphocytes, elevation of serum transaminases and the presence of IgM-specific cytomegalovirus antibodies with a significant rise of IgG-type antibodies as tested by indirect immunofluorescence. The patient's last menstrual period occurred 16 days after defervescence and she gave birth to an apparently normal female term infant with an Apgar score of 10 who has not shed virus in her urine during the first six months of life.