[The immunology of Crohn Disease (author's transl)]

Although the incidence of Crohn disease seems to be increasing, it's etiology remains unknown. The search for immunological mechanisms has been extensively carried out with conflicting results. At the present, most studies provide evidence suggesting a possible immunological dysfunction. Another interesting point is the possible role of an oxygen dependant cytotoxic activity of phagocytes in inflammatory processes, and particularly in Crohn disease.