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Related Experiment Videos

Border disease virus isolation from postpartum ewes.

S M Niemi, J F Evermann, E M Huffman

    American Journal of Veterinary Research
    |January 1, 1982
    PubMed
    Summary
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    Border disease virus, antigenically related to bovine viral diarrhea virus (BVDV), was prevalent in Targhee sheep. Many lambs were seropositive, with some born to seronegative ewes, suggesting immunotolerance.

    Area of Science:

    • Veterinary Virology
    • Sheep Health
    • Epidemiology

    Background:

    • Border disease virus (BDV) is antigenically related to bovine viral diarrhea virus (BVDV).
    • Understanding BDV prevalence is crucial for sheep flock health management.

    Purpose of the Study:

    • To determine the prevalence of BDV in a Targhee sheep flock in southern Idaho.
    • To investigate the serologic relationship between ewes and their neonatal lambs regarding BVDV.

    Main Methods:

    • Serologic testing of ewes and lambs for BVDV antibodies.
    • Virologic isolation of viruses from ewes.
    • Direct immunofluorescence for viral identification.

    Main Results:

    • 29% of ewes and 51% of lambs were seropositive for BVDV.

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  • 35% of seropositive lambs were from seronegative ewes.
  • Eleven BVDV-related viruses were isolated from ewes, six from seronegative dams.

    • Conclusions:

    • High seroprevalence of BVDV in the studied sheep flock.
    • Evidence suggests potential BVDV immunotolerance in ewes, impacting lamb serostatus.
    • BDV circulation in sheep warrants further investigation.