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Related Experiment Videos

Male breast at autopsy.

J A Andersen, J B Gram

    Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. Section A, Pathology
    |May 1, 1982
    PubMed
    Summary

    Gynecomastia, a common male breast condition, was found in 55% of 100 autopsies, often without clinical signs. Seven cases showed atypical hyperplasia, potentially indicating early cancer.

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    Area of Science:

    • Pathology
    • Histology
    • Male Breast Health

    Background:

    • Gynecomastia is a common condition in men.
    • Clinical detection of gynecomastia can be challenging.
    • Histological examination is crucial for accurate diagnosis.

    Purpose of the Study:

    • To determine the prevalence of gynecomastia in an unselected male autopsy series.
    • To investigate the histological features of gynecomastia.
    • To identify any associated pathological changes, such as atypical hyperplasia.

    Main Methods:

    • A consecutive series of 100 male autopsies were analyzed.
    • Breasts were totally extirpated and subjected to detailed histological investigation.
    • Cases were classified based on the phase of gynecomastia (healed or active).

    Main Results:

    • Gynecomastia was histologically confirmed in 55% of cases (55 out of 100).
    • The majority of cases (48/55) showed healed gynecomastia; seven were in an active phase.
    • Seven cases exhibited severe intraductal epithelial hyperplasia (3 pagetoid, 4 cribriform), classified as atypical hyperplasia/early intraductal carcinoma.

    Conclusions:

    • Gynecomastia is highly prevalent in the male population, frequently occurring bilaterally and often without clinical manifestation.
    • Histological examination revealed a significant incidence of atypical hyperplastic changes, suggesting early neoplastic processes.
    • These findings highlight the importance of routine histological examination in male breast tissue, even in the absence of clinical symptoms.

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