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Related Experiment Videos

Recurring digital fibroma.

G Mortimer, A A Gibson

    Journal of Clinical Pathology
    |August 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Recurring digital fibroma, a distinct tumor, was studied in seven cases. These tumors are characterized by specific inclusion bodies and are confirmed to be neoplastic lesions of the myofibroblast.

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    Area of Science:

    • Dermatopathology
    • Surgical Pathology
    • Oncology

    Background:

    • Recurring digital fibroma is a distinct tumor with classical clinical, macroscopic, and microscopic features.
    • Pathognomonic round, eosinophilic cytoplasmic inclusion bodies are characteristic of this tumor.

    Purpose of the Study:

    • To confirm the nature of recurring digital fibroma.
    • To investigate the origin of the inclusion bodies within the tumor cells.

    Main Methods:

    • Clinical, macroscopic, and microscopic examination of seven cases.
    • Ultrastructural analysis of tumor cells and inclusion bodies.

    Main Results:

    • All seven cases exhibited classical features of recurring digital fibroma.

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  • Ultrastructural analysis confirmed a myofibroblastic origin for all cases.
  • Inclusion bodies were suggested to be derived from contractile protein.

    • Conclusions:

    • Recurring digital fibroma is established as a neoplastic lesion.
    • The tumor originates from myofibroblasts.
    • Inclusion bodies are likely related to contractile protein within the myofibroblast.