[Role of catecholamine in activating glycogenolysis in experimental myocardial infarct complicated by ventricular...

The experiments on anaesthetized dogs have shown that with artificial ventilation and open chest adrenalin in arrhythmogenic and nonarrythmogenic doses enhances glycogenolysis in the heart proportionally to the dose used Block of beta-adrenergic receptors by propranolol decreased the activation of glycogenolysis in the ischaemic zone and the frequency of ventricular fibrillation after occlusion of the coronary artery. Exhaustion of noradrenaline reserves by reserpin does not influence the intensity of glycogenolysis and the frequency of fibrillation in the acute period of myocardial infarction. It is believed that the activation of glycogenolysis in experimental myocardial infarction is related to the action of adrenalin.