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Naloxone antagonism of the thermoregulatory effects of phencyclidine
Science (New York, N.Y.)
|September 24, 1982
Abstract:
Phencyclidine elicits hyperthermia at low doses and hypothermia at high doses in rats. Naloxone antagonizes both effects. Phencyclidine's effects on thermo-regulation are probably mediated by an interaction with a mu opiate receptor.