[Isolation of Vibrio eltor mutants producing melanin and the mapping of the mel locus using transposons]
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Updated: Oct 13, 2026

12:13
TransFLP — A Method to Genetically Modify Vibrio cholerae Based on Natural Transformation and FLP-recombination
Published on: October 8, 2012
Abstract:
Melanin-producing V. eltor mutants obtained by means of the transposon which determines resistance to tetracycline (Tn 10) are described. Gene mel is believed to be localized on the chromosome of V. eltor in the region of markers his trp met ura rif arg ilv.
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In-vitro Mutagenesis (Gene Knockouts)
To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
In vitro Mutagenesis
To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.

