[Effect of the oral administration of ranitidine on pituitary secretion]

The acute oral administration of Ranitidine (200 mg.) does not determine significant variations in the plasma levels of PRL, LH, FSH, HGH, ACTH and Cortisol. This fact seems to exclude a vigorous action of the drug, in therapeutic doses, on the hypothalamo-pituitary axis. Furthermore, it cannot be excluded that the chronic administration of Ranitidine cam determine significant variations in the hormones themselves.