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Glomus tumor: a clinicopathologic and electron microscopic study.

M Tsuneyoshi, M Enjoji

    Cancer
    |October 15, 1982
    PubMed
    Summary
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    Glomus tumors, often painful and typically found on fingers, are characterized by vascular spaces and epithelioid cells. Clinicopathologic findings suggest they are mesodermal lesions, not true neoplasms.

    Area of Science:

    • Pathology
    • Dermatology
    • Surgical Oncology

    Background:

    • Glomus tumors are rare soft tissue neoplasms.
    • They most commonly occur on the fingers and are often associated with pain.

    Purpose of the Study:

    • To investigate the clinicopathologic features of glomus tumors.
    • To determine the origin and nature of glomus tumors.

    Main Methods:

    • Clinicopathologic analysis of 63 glomus tumor cases.
    • Histological examination of tumor morphology.
    • Electron microscopy to identify tumor cell type.

    Main Results:

    • Glomus tumors most frequently occurred on fingers (35 cases), often as subungual nodules (26 cases).

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  • Pain was a predominant symptom in 62 out of 63 patients.
  • Histologically, tumors were classified into vascular (29), myxoid (23), and solid (11) types.
  • Electron microscopy confirmed tumor cells as smooth-muscle cells.

    • Conclusions:

    • Glomus tumors exhibit distinct clinicopathologic characteristics.
    • The findings support the hypothesis that glomus tumors are tumor-like lesions arising from mesodermal dysplasia rather than true neoplasms.