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Moyamoya disease in children
Southern Medical Journal
|March 1, 1978
Abstract:
A review of the recent Mayo Clinic experience with stroke in children having cerebral angiography revealed five patients with moyamoya disease. The disease commonly presents as recurrent strokes and only rarely as a seizure disorder. The angiographic pattern suggests that the telangiectasia characteristic of this condition represents normally present dilated vessels.
Insights
Moyamoya disease, a rare condition causing recurrent strokes in children, was reviewed in five pediatric patients. Angiography suggests characteristic telangiectasias are normally dilated vessels.
Area of Science:
- Neurology
- Pediatric Neurology
- Vascular Neurology
Background:
- Moyamoya disease is a rare, progressive cerebrovascular disorder.
- It typically presents with recurrent ischemic strokes or transient ischemic attacks in children.
- Cerebral angiography is crucial for diagnosis.
Observation:
- A review of Mayo Clinic cases identified five pediatric patients with moyamoya disease.
- The presenting symptom in these cases was primarily recurrent stroke.
- Seizures were an infrequent presentation.
Findings:
- The characteristic angiographic findings of moyamoya disease, specifically telangiectasias, may represent normally present, dilated intracranial vessels.
- This challenges previous understandings of the underlying pathology.
Implications:
- Understanding the nature of these vessels could lead to improved diagnostic criteria.
- Further research into the vascular changes in moyamoya disease is warranted.
- This may influence future treatment strategies for pediatric stroke.