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Computed tomography in malignant fibrous histiocytoma
Journal of Computer Assisted Tomography
|August 1, 1982
Summary
Computed tomography (CT) revealed malignant fibrous histiocytoma (MFH) typically appears as a poorly defined mass with low attenuation. These nonspecific CT findings hinder differentiation from other soft tissue sarcomas.
Area of Science:
- Radiology
- Oncology
- Pathology
Background:
- Malignant fibrous histiocytoma (MFH) is a rare soft tissue sarcoma.
- Accurate diagnosis relies on histopathological examination.
- Radiological features can aid in initial assessment.
Purpose of the Study:
- To describe the computed tomographic (CT) findings in malignant fibrous histiocytoma.
- To evaluate the typical appearance and diagnostic characteristics of MFH on CT scans.
Main Methods:
- Retrospective review of CT scans from 11 patients diagnosed with malignant fibrous histiocytoma.
- Analysis of tumor characteristics including margin definition, attenuation, necrosis, and involvement of adjacent structures.
Main Results:
- Eight primary tumors showed a poorly marginated mass with attenuation lower than normal muscle.
- Central tumor necrosis was observed in three cases.
- Abdominal tumors demonstrated involvement of adjacent soft tissues (3/5) and bone destruction (1/5).
Conclusions:
- The CT appearance of malignant fibrous histiocytoma is nonspecific.
- Differentiation from other soft tissue sarcomas based solely on CT findings is challenging.
- CT is valuable for assessing tumor extent and involvement of adjacent structures.