Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Functioning adrenocortical tumour in a dog.

M E Vince, A D Watson

    Australian Veterinary Journal
    |April 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    A Dachshund diagnosed with hyperadrenocorticism showed worsening symptoms after treatment with o,p-DDD. Necropsy revealed adrenocortical carcinoma with liver metastases, indicating a poor prognosis for advanced cases.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Authentication of beef versus horse meat using 60 MHz 1H NMR spectroscopy.

    Food chemistry·2015
    Same author

    60 MHz <sup>1</sup>H NMR spectroscopy for the analysis of edible oils.

    Trends in analytical chemistry : TRAC·2014
    Same author

    A Hymn for Canada.

    Canadian Medical Association journal·2010
    Same author

    Effectiveness of two statin prescribing strategies with respect to adherence and cardiovascular outcomes: observational study.

    Pharmacoepidemiology and drug safety·2006
    Same author

    Cuboidal W3S4 cluster complexes as new generation X-ray contrast agents.

    Inorganic chemistry·2003
    Same author

    Systemic antibacterial drug use in dogs in Australia.

    Australian veterinary journal·2002
    Same journal

    Basal body temperature as a biomarker of reproductive state in ewes: A multi-method comparison.

    Australian veterinary journal·2026
    Same journal

    Impact of climate on Australian, non-Vector-borne infectious animal diseases: A scoping review.

    Australian veterinary journal·2026
    Same journal

    A 9-year retrospective mortality review of captive orange-bellied parrots (Neophema chrysogaster) in Australia.

    Australian veterinary journal·2026
    Same journal

    Antimicrobial-resistant Staphylococcus aureus isolated from Australian wildlife admitted to a veterinary hospital.

    Australian veterinary journal·2026
    Same journal

    Asymptomatic thrombocytopenia in Akitas: a prospective cross-sectional study of platelet characteristics in an Eastern Australian population.

    Australian veterinary journal·2026
    Same journal

    Partial amputation regrowth of P4 distal digit in an eastern grey kangaroo (Macropus giganteus): a case report.

    Australian veterinary journal·2026
    See all related articles

    Area of Science:

    • Veterinary Medicine
    • Canine Endocrinology
    • Oncology

    Background:

    • Hyperadrenocorticism (Cushing's disease) is a common endocrine disorder in dogs.
    • Clinical signs include polydipsia, polyuria, and abdominal distension.
    • Diagnosis involves clinical signs and laboratory abnormalities.

    Observation:

    • An 11-year-old female Dachshund presented with classic hyperadrenocorticism signs.
    • Initial treatment with o,p'-DDD (mitotane) for 14 days resulted in patient deterioration.
    • Laboratory findings included lymphocytopenia, eosinopenia, hypercholesterolemia, and elevated alkaline phosphatase.

    Findings:

    • Hormonal assays indicated a functional adrenocortical tumor.
    • The patient's poor condition prevented surgical intervention (adrenalectomy).

    Related Experiment Videos

  • Necropsy confirmed adrenocortical carcinoma with hepatic metastases.

    • Implications:

    • This case highlights the challenges in managing hyperadrenocorticism, particularly advanced stages.
    • Early diagnosis and appropriate treatment are crucial for better outcomes.
    • Adrenocortical carcinoma carries a grave prognosis, even with treatment attempts.