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[Still disease in adults]
La Semaine Des Hopitaux : Organe Fonde Par L'Association D'Enseignement Medical Des Hopitaux De Paris
|September 9, 1982
Summary
Adult-onset Still disease, a rare condition, primarily affects women with symptoms like fever, arthritis, and rash. This review covers its key features, hepatic and muscular involvement, and prognosis.
Area of Science:
- Rheumatology
- Internal Medicine
Context:
- Adult-onset Still disease (AOSD) is a rare systemic inflammatory disorder.
- First described by Bywaters in 1971, it is distinct from the childhood form.
- Over one hundred cases have been documented since its initial description.
Purpose:
- To review the clinical and investigative features of adult-onset Still disease.
- To highlight hepatic and muscular involvement and discuss articular prognosis.
- To address ongoing debates regarding management and therapeutic outcomes.
Summary:
- AOSD predominantly affects women, with an average age of onset at 27 years.
- Key manifestations include fever, arthritis, evanescent rash, lymphadenopathy, splenomegaly, and serositis.
- Hepatic dysfunction and myositis are significant considerations, impacting the overall prognosis.
Impact:
- Provides a comprehensive overview of AOSD for clinicians and researchers.
- Emphasizes the importance of recognizing less common manifestations like hepatic and muscular involvement.
- Contributes to the ongoing discussion on optimal treatment strategies and their efficacy.