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Hypertension and neurofibromatosis. Case report
Hypertension (Dallas, Tex. : 1979)
|November 1, 1982
Summary
Neurofibromatosis patients with severe hypertension may have associated tumors. A cerebellar glioblastoma multiforme was found to cause significant blood pressure elevation in a young patient.
Area of Science:
- Pediatric Oncology
- Neurology
- Cardiovascular Medicine
Background:
- Neurofibromatosis is a genetic disorder associated with various tumors.
- Severe hypertension in adolescents requires thorough investigation for underlying causes.
Observation:
- A 14-year-old girl with neurofibromatosis presented with severe hypertension.
- Imaging revealed a cerebellar glioblastoma multiforme and vascular abnormalities including aortic coarctation and renal artery stenosis.
Findings:
- Surgical removal of the cerebellar tumor led to significant improvement in blood pressure.
- The glioblastoma multiforme was implicated as the primary cause of the severe hypertension.
Implications:
- This case highlights the importance of evaluating for intracranial tumors in neurofibromatosis patients with hypertension.
- Comprehensive assessment for vascular lesions and tumors is crucial in managing hypertension in this population.