Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Candidiasis in captive cetaceans.

J L Dunn, J D Buck, S Spotte

    Journal of the American Veterinary Medical Association
    |December 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Ketoconazole and levamisole treatments showed promise for disseminated Candida albicans infections in captive cetaceans. However, nystatin proved ineffective, highlighting the need for targeted antifungal strategies in marine mammals.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Seroprevalence of Brucella antibodies in harbor seals in Alaska, USA, with age, regional, and reproductive comparisons.

    Diseases of aquatic organisms·2017
    Same author

    Comparison ofin Situ andin Vitro survival ofCandida albicans in seawater.

    Microbial ecology·2013
    Same author

    Occurrence ofCandida albicans in fresh gull feces in temperate and subtropical areas.

    Microbial ecology·2013
    Same author

    Precise orientation of a single C60 molecule on the tip of a scanning probe microscope.

    Physical review letters·2012
    Same author

    Bandwidth and tuning range of an ArF laser measured by 1 + 1 resonantly enhanced multiphoton ionization of NO.

    Applied optics·2010
    Same author

    Deep intra-uterine artificial inseminations using cryopreserved spermatozoa in beluga (Delphinapterus leucas).

    Theriogenology·2010
    Same journal

    Acute-onset neurologic signs in an indoor/outdoor domestic shorthair cat.

    Journal of the American Veterinary Medical Association·2026
    Same journal

    Progressive exophthalmos and strabismus in a 4-year-old Jersey steer.

    Journal of the American Veterinary Medical Association·2026
    Same journal

    Orchiectomy in horses: closed technique and primary closure of the incision.

    Journal of the American Veterinary Medical Association·2026
    Same journal

    Stranguria in a 3-month-old Holstein-Friesian heifer.

    Journal of the American Veterinary Medical Association·2026
    Same journal

    Caudal vena cava-to-aorta ratio in hemodynamically stable and unstable client-owned rabbits.

    Journal of the American Veterinary Medical Association·2026
    Same journal

    Dogs with intrahepatic portal hypertension of congenital cause have distinct diagnostic findings compared to dogs with chronic hepatitis-related portal hypertension.

    Journal of the American Veterinary Medical Association·2026
    See all related articles

    Area of Science:

    • Veterinary Medicine
    • Marine Biology
    • Mycology

    Background:

    • Disseminated Candida albicans infections pose a significant health risk to captive cetaceans.
    • Effective treatment protocols for candidiasis in marine mammals are crucial for animal welfare.

    Observation:

    • Four captive cetaceans exhibited signs or suspicion of disseminated Candida albicans infections.
    • Clinical signs regressed in an Atlantic bottlenose dolphin treated with ketoconazole and levamisole.
    • Candidiasis shedding was eliminated in a belukha whale using a higher dose of ketoconazole.

    Findings:

    • Nystatin treatment was unsuccessful in a harbor porpoise and a pilot whale, both of which succumbed to disseminated candidiasis.
    • Ketoconazole, particularly at a higher dosage, demonstrated efficacy in treating Candida albicans infections in cetaceans.

    Related Experiment Videos

  • Levamisole hydrochloride, when used in conjunction with ketoconazole, contributed to positive treatment outcomes.

    • Implications:

    • These findings suggest that ketoconazole and levamisole may be valuable components of antifungal treatment regimens for cetaceans.
    • The ineffectiveness of nystatin underscores the importance of selecting appropriate antifungal agents based on species and pathogen susceptibility.
    • Further research into Candida albicans pathogenesis and treatment in marine mammals is warranted to improve conservation and veterinary care.