Identification of basic drugs in urine by dual fused silica capillary column GC

A method for analyzing urine for the presence of basic drugs and their metabolites using two fused silica capillary columns is described along with operating conditions and column characteristics. Urine extracts were injected into a gas chromatograph equipped with nitrogen phosphorous detectors (GC/NPD) and two capillary columns, housed in a single injection port. The injected material was simultaneously chromatographed in each column. Identification of unknowns was done using relative retention times.