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Related Experiment Videos

Urinary infection in boys.A three-year prospective study.

R J Hallett, L Pead, R Maskell

    Lancet (London, England)
    |November 20, 1976
    PubMed
    Summary
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    Urinary tract infections in boys may originate from the prepuce or urethra, differing from girls. Recurrence is rare unless gram-negative bacteria persist in the urethra.

    Area of Science:

    • Pediatric Urology
    • Infectious Diseases
    • Microbiology

    Background:

    • Urinary tract infections (UTIs) are common in children.
    • Understanding the source and natural history of UTIs in boys is crucial for effective management.
    • Previous studies often focused on girls, leaving a gap in knowledge for pediatric male populations.

    Purpose of the Study:

    • To prospectively investigate the clinical and microbiological aspects of urinary tract infections in boys.
    • To identify the primary source of infection and factors influencing recurrence in male pediatric patients.
    • To compare the natural history of UTIs in boys with that observed in girls.

    Main Methods:

    • A three-year prospective study of 73 boys with bacteriuria and UTI symptoms.

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  • Inclusion of clinical, radiological, and microbiological investigations.
  • Monthly monitoring of preputial flora and midstream urine cultures.

    • Main Results:

    • 30% of boys had urinary tract abnormalities; 6% showed pyelonephritic changes.
    • Proteus species were the predominant infecting organisms.
    • Preputial/urethral flora suggested these as infection sources, unlike the bowel in girls. 70% had no recurrence.

    Conclusions:

    • The natural history of UTIs in boys appears distinct from that in girls.
    • The prepuce and urethra are likely primary sources of infection in boys.
    • Recurrence may be linked to persistent urethral gram-negative organisms, highlighting urethral infection's significance.