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Sympathetic uveitis after trauma and vitrectomy.

M L Lewis, D M Gass, W H Spencer

Archives of Ophthalmology (Chicago, Ill. : 1960)

|February 1, 1978

Summary

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Sympathetic uveitis after eye trauma and vitrectomy can initially mimic placoid pigment epitheliopathy. Histopathology revealed choroidal granulomas and Dalen-Fuchs nodules as the cause.

Area of Science:

Ophthalmology
Pathology

Background:

Sympathetic uveitis is a rare, bilateral inflammatory condition affecting the uvea.
It typically occurs after ocular trauma or surgery.
Pars plana vitrectomy is a common surgical procedure for various retinal conditions.

Observation:

A case of sympathetic uveitis following trauma and pars plana vitrectomy presented with early retinal, retinal pigment epithelium, and choroidal lesions.
These posterior focal lesions resembled acute posterior multifocal placoid pigment epitheliopathy.
Similar lesions were observed on gross examination of the affected eye.

Findings:

Histopathological examination identified focal choroidal granulomas and overlying Dalen-Fuchs nodules as the cause of these lesions.
Four additional patients with sympathetic ophthalmia after trauma and vitrectomy were also identified.

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Implications:

This presentation expands the understanding of the early clinical manifestations of sympathetic uveitis.
Recognizing these placoid-like lesions is crucial for timely diagnosis and management of sympathetic uveitis.
The findings highlight the importance of histopathological correlation in diagnosing post-surgical sympathetic ophthalmia.